The nanobody is an antibody fragment consisting of a single monomeric variable antibody domain. Nanobodies are the smallest functional antigen-binding fragments.
We have newly released a secondary antibody, alpaca anti-rabbit IgG FC recombinant VHH (HRP), which is a monoclonal Nanobody.
This nano secondary antibody has multiple advantages.
Fewer Animal ethics disputes:
The secondary antibodies use microbial fermentation for large-scale production, greatly reduced the number of animals used for secondary antibody production
Recombination techniques are used to reduce batch-to-batch differences.
High specificity :
Nanobody has no FC terminal. It could eliminate non-specific binding between Fc and Fc receptor on cells (such as macrophages, dendritic cells, neutrophils, NK cells and B cells) , and does not interfere with anti-Fc mediated antibody detection.
Higher resolution imaging :
The smaller size of Alpaca anti-rabbit Fc, recombinant VHH enables it penetrate tissues more efficiently.And it decreases the distance between the epitope and label.
The Alpaca anti-rabbit Fc, recombinant VHH could be incubated together with the rabbit primary antibody.
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